ENGINEERED HUMAN PLURIPOTENT STEM CELL-DERIVED NATURAL KILLER CELLS WITH PD-L1 RESPONSIVE IMMUNOLOGICAL MEMORY FOR ENHANCED IMMUNOTHERAPEUTIC EFFICACY

Adoptive chimeric antigen receptor (CAR)-engineered natural killer (NK) cells have shown promise in treating various cancers.However, limited immunological memory and access to sufficient numbers of allogenic donor cells have hindered their broader preclinical and clinical applications.Here, we first assess eight different CAR constructs that use a

Abstract Background We present a dashboard for the evaluation of the impact of school closures on children and parents during the first wave of the COVID pandemic in 2020 on the various components of wellbeing.Methods Starting from an explorative literature search by a team of experts from diverse fields (e.g., epidemiology, virology, psychology, e

Conservation environment with high humidity content or exposure to liquid water are directly linked to degradation of cellulosic materials, such as paper and fabrics.This research had as main objective the development of formulations based on two water-repellent products commercially available: a fluoroacrylic co-polymer and a Mushroom Vapes polydi

(1) Background: ICIP territorialization has been a trend in European countries.Evidence shows that local monitoring is effective in the process of social inclusion; however, territorial differences may cause different results in social and professional trajectories.This systematic and narrative review aims to understand the territorialized elements